ALT | normal |
---|---|
anti-HEV IgM | - |
anti-HEV IgG | - |
HEV RNA | (+) |
Symptoms | - |
(…) = potentially present
ALT | (elevated) |
---|---|
anti-HEV IgM | (+) |
anti-HEV IgG | (+) |
HEV RNA | + |
Symptoms | (+) |
(…) = potentially present
ALT | elevated |
---|---|
anti-HEV IgM | + |
anti-HEV IgG | +, rising |
HEV RNA | (+) |
Symptoms | + |
(…) = potentially present
ALT | normal |
---|---|
anti-HEV IgM | (+) |
anti-HEV IgG | + |
HEV RNA | - |
Symptoms | - |
(…) = potentially present
Adapted from:
a) for use on the cobas® e 411 analyzer and the cobas® e 601 / 602 modules;
b) for use on the cobas® e 402 and cobas® e 801 analytical units
c) intended for use to screen donor samples for HEV RNA in plasma samples from individual human donors, including donors of whole blood, blood components (red cells, platelets, and plasma), and other living donors; not intended for use as an aid in diagnosis for HEV; for use on the cobas® 6800/8800 Systems
Adapted from:
Perform anti-HEV IgM and
anti-HEV IgG tests in parallel
Past HEV infection
No evidence of HEV infection
Current acute HEV infection
Advise to maintain good personal hygiene to minimize spread of the infection. For management of infected patients (especially at-risk groups like patients with underlying chronic liver disease or pregnant women), refer to clinical practice guidelines.
Recent acute HEV infection
For management of infected patients (especially at-risk groups like patients with underlying chronic liver disease or pregnant women), refer to clinical practice guidelines.
Early acute HEV infection
Advise to maintain good personal hygiene to minimize spread of the infection. For management of infected patients (especially at-risk groups like patients with underlying chronic liver disease or pregnant women), refer to clinical practice guidelines.
No acute HEV infection
Anti-HEV IgM reactivity alone is not diagnostic of acute HEV infection.
anti-HEV IgM test = ...
anti-HEV IgG test = ...
anti-HEV IgM test = positive
anti-HEV IgG test = positive
Acute or recent HEV infection.
Perform HEV RNA test to confirm the stage of acute HEV infection.